Histopathological Spectrum of Urothelial Lesions

Introduction Tumous of the bladder are one of the most common urological lesions encountered in clinical practice. Cancer of the urinary bladder is the 7 th most common cancer worldwide which constitutes for 90% of all primary tumors of the bladder.The present study was undertaken to review the histopathological lesions of the bladder, determine the age, sex, incidence of these tumours along with grading and staging. Objectives:1.To identify the various histopathological lesions of the urinary bladder 2.To determine the demographic characteriatics of the bladder lesions. Methods: A one year prospective study of the urothelial lesions was carried out in the Department of Pathology, Narayana Medical College, Nellore. Related clinical history of all these cases were recorded. Results: The present study was conducted over a period of one year during which a total of 48 lesions were evaluated. Malignant lesions were more common with a male predominance. The peak age of incidence of the lesions was 61-70 years. Hematuria was the most common presenting complaint. High grade invasive urothelial carcinoma was the most common histopathological lesion encountered in our study. Conclusion: Bladder cancer has become very common nowadays. These tumors when presented in the advanced stage have an overall poor survival rate. Pathological grading plays a key role in the prognosis of these tumors.